Is the Clock Drawing Test
Appropriate for screening for Mild Cognitive Impairment? – Results
of the German Study on Ageing, Cognition and Dementia in Primary Care Patients
(AgeCoDe)
Claudia Sikorski
Melanie
Luppa
Tobias Luck
Lena Ehreke
Institut für Sozialmedizin, Arbeitsmedizin und Public Health (ISAP),
Arbeitsgruppe Public Health: Epidemiologie und Versorgungsforschung
Universität Leipzig
Siegfried Weyerer, Sandra
Eifflaender-Gorfer
Central Institute for Mental Health, Mannheim
Birgit Wiese, Medizinische Hochschule
Hannover, Institut für Biometrie, Hannover
Dagmar Weeg, Julia Olbrich
Department of Psychiatry, Technical University
of Munich, Munich
Hendrik van den Bussche, Cadja Bachmann, Marion Eisele
Institute for General
Medicine, University Medical Centre Hamburg-Eppendorf, Hamburg
Wolfgang Maier, Frank Jessen
Department of Psychiatry, University of Bonn,
Bonn
Angela Fuchs, Michael Pentzek
Department of General Practice, University
Medical Centre, Düsseldorf
Matthias C. Angermeyer, Steffi G. Riedel-Heller
Institute of Social
Medicine, Occupational Health and Public Health, Leipzig
Hans-Helmut König,
Department of Medical Sociology and Health Economics, University Medical Center
Hamburg-Eppendorf, Hamburg
1 . Zielsetzung/Fragestellung
Individuals with Mild Cognitive Impairment (MCI) are at high risk to develop
dementia and are a target group for preventive interventions. Therefore, research
aims at diagnosing MCI at an early stage with short, simple and easily administrable
screening tests. Due to the fact that the Clock Drawing Test (CDT) is widely
used to screen for dementia, it is questionable whether the CDT is suited to
screen for MCI.
2. Materialien/Methoden
3,198 primary care patients aged 75+ were divided into two groups according
to their cognitive status, assessed by comprehensive neuro-psychological testing:
individuals without MCI and individuals with MCI. The CDT-scores, evaluated
by the scoring system of Sunderland et al. [1], of both groups were compared.
Multivariate analyses were calculated as well as sensitivity, and the specificity
of the CDT to screen for MCI were reported.
3. Ergebnisse
Significant differences were found for CDT-results: MCI-patients obtained worse
results than cognitively unimpaired subjects. CDT has a significant impact
on the diagnosis of MCI. However, sensitivity and specificity as well as ROC
analyses are not adequate, meaning CDT could not be named as an exact screening
tool.
Limitations: Applying different CDT-versions of administration and scoring
could yield different results.
4. Zusammenfassung/Schlussfolgerung
CDT did not achieve the quality to screen individuals for MCI